Stock performances of European biotech companies: status at the end of Q3 2019

The ranking of the 9-month 2019 stock performance is shown below. 42% of the field was in positive territory at the end of September, and 58% in negative territory.
As one can see, the top tail of the vertical waterfall plot is fully red (UK/IE cluster). Consistently with previous comments, there is a lot of blue (France) in the bottom third of the plot.

Q3 2019 Highlights/Impact Events:
Gainers: Silence Therapeutics signed a deal with Mallinckrodt, Okyo disclosed a preclinical proof-of-concept in dry ARMD, Oasmia changed the management who makes peace with the main shareholder, phase 1a passed for Cyxone's T20K, Amryt resumed trading after a suspension due to the merger with Aegerion.
Decliners: Mologen's phase 3 of lefitolimod failed in maintenance treatment of CRC, Biophytis stock fall continued, no more hope for Motif Bio's iclaprim on the short term, FDA said no to Pharnext for a filing of PXT3003 (new trial required), IRLAB IRL790 phase 2a failed in PD-LID, mixed PK data for Gabather's GT-002 FIH trial, Alligator regained rights of ADC-1013 from Janssen.

European Biotech Q3 Perf. (%) - n=149/Nuevolution de-listed

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	Company	Country	Q3 Var%
1	Silence Therapeutics	UK	132.9
2	Okyo Pharma	UK	125.0
3	Oasmia Pharma.	SE	115.2
4	Cyxone	SE	83.4
5	Amryt Pharma	IE	76.4
6	Pharming Group	NL	69.9
7	Shield Therapeutics	UK	66.8
8	Hybrigenics	FR	36.4
9	A1M Pharma	SE	33.0
10	Redx Pharma	UK	31.1
11	Acacia Pharma	UK	28.8
12	Saniona	DK	28.3
13	NeuroVive	SE	27.6
14	Mereo BioPharma	UK	26.0
15	Innate Pharma	FR	25.7
16	Galapagos	BE	23.2
17	Zealand Pharma	DK	22.2
18	Basilea Pharma.	CH	21.3
19	Molecular Partners	CH	19.8
20	Morphosys	DE	19.7
21	BergenBio	NO	19.5
22	Camurus	SE	16.5
23	ReNeuron	UK	15.7
24	Herantis Pharma	FI	15.4
25	Genmab	DK	15.2
26	Mithra Pharmaceuticals	BE	15.1
27	Bavarian Nordic	DK	13.9
28	Indivior	UK	13.7
29	Inventiva	FR	11.5
30	Addex Therapeutics	CH	11.5
31	Poxel	FR	11.3
32	ASIT biotech	BE	10.9
33	Idorsia Ltd	CH	10.0
34	Scancell Holdings	UK	7.4
35	4D Pharma	UK	6.9
36	Probiodrug	DE	6.5
37	DBV Technologies	FR	6.3
38	MedinCell	FR	5.6
39	ABIVAX	FR	5.0
40	Paion	DE	4.6
41	PCI Biotech	NO	3.6
42	Oncodesign	FR	2.2
43	OSE Pharma	FR	1.9
44	Alzecure Pharma	SE	1.4
45	PharmaMar	ES	1.1
46	Lidds	SE	0.9
47	Karessa Pharma	SE	0.0
48	Molmed	IT	0.0
49	Nicox	FR	0.0
50	Vectura	UK	-0.6
51	GeNeuro	CH	-1.0
52	Midatech Pharma	UK	-1.3
53	Medivir	SE	-2.5
54	Alzinova	SE	-2.6
55	Formycon	DE	-2.9
56	XSpray	SE	-2.9
57	Orphazyme	DK	-3.1
58	Isofol Medical	SE	-5.3
59	Combigene	SE	-5.7
60	BioInvent Internat.	SE	-5.8
61	XBrane Biopharma	SE	-5.9
62	Kancera	SE	-6.0
63	Quantum Genomics	FR	-6.4
64	Ascelia	SE	-6.6
65	PledPharma	SE	-7.8
66	Active Biotech	SE	-8.4
67	Advicenne	FR	-8.4
68	Valneva	FR	-8.8
69	Cerenis Therapeutics	FR	-8.8
70	Faron Pharma.	FI	-9.1
71	Nordic Nanovector	NO	-9.2
72	Summit Therapeutics	UK	-9.5
73	Cassiopea	IT	-9.5
74	Bone Therapeutics	BE	-9.5
75	Genkyotex	CH	-9.6
76	AB Science	FR	-9.8
77	Asarina Pharma	SE	-10.1
78	Diamyd Medical	SE	-10.2
79	Vicore Pharma	SE	-10.4
80	Newron Pharma.	IT	-10.6
81	Allergy Therapeutics	UK	-10.7
82	Lysogene	FR	-11.1
83	Klaria Pharma	SE	-11.1
84	Diurnal Group	UK	-11.3
85	Sareum	UK	-11.4
86	Sprint Bioscience	SE	-11.6
87	Gensight Biologics	FR	-11.7
88	Immupharma	UK	-11.7
89	Hemogenyx	UK	-11.9
90	Celyad	BE	-12.6
91	ObsEva SA	CH	-14.3
92	4SC	DE	-14.3
93	Santhera Pharma.	CH	-14.5
94	Cosmo Pharma.	IT	-14.8
95	Corline Biomedical	SE	-15.1
96	ArGEN-X	BE	-15.5
97	Infant Bacterial Ther.	SE	-15.5
98	Xintela	SE	-15.6
99	Nanobiotix	FR	-16.4
100	Genfit	FR	-16.5
101	Targovax	NO	-16.7
102	Cantargia	SE	-16.8
103	Evotec	DE	-16.9
104	BioArtic	SE	-17.0
105	Evgen Pharma	UK	-17.1
106	Oryzon Genomics	ES	-17.4
107	Medigene	DE	-17.8
108	Heidelberg Pharma	DE	-17.9
109	Verona Pharma	UK	-18.8
110	Calliditas Therapeutics	SE	-19.1
111	Immunicum	SE	-19.4
112	Oncopeptides	SE	-19.4
113	Tiziana Life Sciences	UK	-20.6
114	Transgene	FR	-20.8
115	Onxeo	FR	-21.1
116	Oxford Biomedica	UK	-21.9
117	Oncology Venture	DK	-21.9
118	ValiRx	UK	-22.2
119	Sensorion	FR	-22.6
120	Hansa Medical	SE	-24.8
121	InDex Pharma	SE	-24.9
122	Noxxon Pharma	DE	-25.0
123	Orexo	SE	-25.0
124	Biofrontera	DE	-25.2
125	Annexin Pharma.	SE	-25.5
126	Synairgen	UK	-25.5
127	CytoTools	DE	-26.2
128	Promore Pharma	SE	-27.2
129	Cellectis	FR	-30.3
130	Erytech Pharma	FR	-30.5
131	Neovacs	FR	-30.8
132	Avacta	UK	-31.4
133	N4 Pharma	UK	-31.6
134	Oxurion	BE	-31.9
135	Kiadis Pharma	NL	-32.7
136	Crossject	FR	-33.3
137	co.don	DE	-38.0
138	Adocia	FR	-40.7
139	Theranexus	FR	-45.2
140	Polyphor	CH	-45.6
141	Nuformix	UK	-46.9
142	Destiny Pharma	UK	-49.7
143	Alligator Bioscience	SE	-53.0
144	Gabather	SE	-53.4
145	IRLAB Therapeutics	SE	-55.4
146	Pharnext	FR	-59.3
147	Motif Bio	UK	-63.5
148	Biophytis	FR	-64.9
149	Mologen	DE	-71.6